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Imatinib Mesylate Side effects

Side effects of Imatinib Mesylate and TKIs in general vary, although most of them are considered minor. A decreased in white blood cells is common, and can potentially lead to increased levels of infection within those taking them. Decreased platelet counts can also occur, leading to tarry stools and some mild bleeding in the digestive tract. Nausea or vomiting can also occur, although this can sometimes be reduced by ingesting the pills with a meal and a full glass of water.

Some other side effects that are more mild than those listed above are those that are quite common with many forms of cancer treatments, such as diarrhea, heartburn, headaches, muscle cramps, fluid retention which leads to swelling (this is often most apparent around the eyes) and some rashes developing on the body.

The main major side effects, which are fortunately less common than the above, fall into three main areas. Firstly, some TKIs can lead to liver problems, although this is typically more common amongst those taking Sunitinib rather than Imatinib Mesylate. Secondly, some TKIs have been known to cause depression in users. They can also, on occasion, increase the risk of pulmonary arterial hypertension, a heart condition.

Important precautions about Imatinib Mesylate

It is worth noting, of course, that Imatinib Mesylate will only be taken by a patient under the strict supervision of an oncologist or hematologist in order to monitor any potential side effects that develop. Should any issues arise, the doctor treating the patient will then suggest an alternative form of TKI, or perhaps a different cancer treatment altogether.

As a general rule, Imatinib Mesylate is taken as a pill that can be directly swallowed with water and a meal, meaning that many cancer patients prefer it as a form of treatment. It is certainly less invasive than many other forms of treatment.

Needless to say, the effects of cancer treatments vary substantially from patient to patient, which is why it is important to ensure that anyone undergoing treatment remains in constant contact with their doctor to make sure that any negative effects can be dealt with as soon as possible. Imatinib Mesylate remains an effective form of treatment for various forms of cancer, and as such is an essential part of the modern oncologist's armory.