New study explains why the obese have higher rates of depression

Experts have known that obese individuals are more likely to require a prescription to buy Paxil to treat symptoms of depression than slimmer people. A new study may help explain why this association between obesity and depression exists.

Investigators from the University Hospital of Montreal Research Centre fed groups of mice varying diets and analyzed the brain responses in the animals. The team found that high-fat foods cause the release of dopamine, a neurotransmitter that is responsible for rewarding feelings.

The researchers pointed out that this is essentially the same effect that is caused by many illicit drugs. The inevitable withdrawal of dopamine, or the "come down," is also the same. Over time, this can take a toll on the brain and lead to the development of depression.

"Data shows that obesity is associated with increased risk of developing depression, but we have very little understanding of the neural mechanisms and brain reward patterns that link the two," said lead researcher Stephanie Fulton. "We are demonstrating for the first time that the chronic consumption of palatable, high-fat diets has pro-depressive effects."

The findings suggest that altering eating habits may help obese individuals reduce their risk of developing depression and requiring a prescription to buy Paxil.