Researchers find process that leads to development of arthritic condition

A team of researchers from the Hospital for Special Surgery in New York has identified a cellular process that may play a central role in the development of rheumatoid arthritis. The findings could lead to the development of new medications that prevent the painful joint condition altogether.

The researchers found that variations in a cellular process known as the Notch pathway lead to malfunctions in immune cells. These cells then start attacking joint material, which leads to the destruction of collagen and the pain associated with arthritis.

The finding could represent a major breakthrough in the prevention of arthritis. Variations in the Notch pathway have previously been implicated as risk factors for certain forms of cancer, and researchers are currently working to develop medications that lead to regulation of this cellular process. These same drugs could be used to prevent the development of rheumatoid arthritis.

Currently, one of the best treatments for rheumatoid arthritis is a prescription to buy Celebrex. This medication alleviates the inflammation associated with the condition and reduces pain, but it does not prevent the development of the joint problem.